2,3-Diphosphoglycerate

A highly anionic organic phosphate which is present in human red blood cells at about the same molar ratio as hemoglobin. It binds to deoxyhemoglobin but not the oxygenated form, therefore diminishing the oxygen affinity of hemoglobin. This is essential in enabling hemoglobin to unload oxygen in tissue capillaries. It is also an intermediate in the conversion of 3-phosphoglycerate to 2-phosphoglycerate by phosphoglycerate mutase (EC 5.4.2.1). (From Stryer Biochemistry, 4th ed, p160; Enzyme Nomenclature, 1992, p508)

Also Known As:

2,3 Bisphosphoglycerate; 2,3 Diphosphoglycerate; 2,3-Diphosphoglycerate, (D)-Isomer; Glycerate 2,3-Bisphosphate; 2,3 Diphosphoglyceric Acid; 2,3-Bisphosphate, Glycerate; 2,3-Bisphosphoglycerate; 2,3-DPG; 2,3-Diphosphoglyceric Acid

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Sugar Acids: 4
      - Glyceric Acids
        Diphosphoglyceric Acids
        2,3-Diphosphoglycerate: 512
  - Acyclic Acids
    - Sugar Acids: 4
      - Glyceric Acids
        Diphosphoglyceric Acids
        2,3-Diphosphoglycerate: 512
- Organophosphorus Compounds: 300
  - Organophosphates: 1942
    - Diphosphoglyceric Acids
      - 2,3-Diphosphoglycerate: 512
Carbohydrates: 22023
- Sugar Acids: 4
  - Glyceric Acids
    - Diphosphoglyceric Acids
      - 2,3-Diphosphoglycerate: 512

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